CRT 2020 Highlights publication: Swati Mukherjee, MD, discussed gender-specific issues in coronary artery disease. She cited a recently published study showing that only one-third of revascularization patients (either with percutaneous coronary intervention or coronary artery bypass grafting) are women, and that the percentage has fallen over time. Another study shows that door-to-balloon time is more than 10 minutes longer for women than for men, and women are less likely to receive evidence-based treatment than men.

http://www.crtmeeting.org/highlights 

Gender-Neutral Part-Time/Flexible Training Options, Work-Life Balance and Gender Parity in Advanced Cardiology Training: The 2019 Survey of the FRACP Advanced Cardiology Trainees and Recent Graduates A. Leet, A. Beale, L. Segan, A. Castles, C. Cheshire, S. Biswas, S. Gutman, S. Mukherjee, M. Watts, M. Richardson, S. Lockwood, M. Freeman, L. Selkrig, S. Zaman 

Plasma heme oxygenase-1 level is associated with reduction in extracellular matrix expansion in peri infarct region post acute myocardial infarction S.Mukherjee, W.Chan, B.Kingwell, A.Natoli, S.Duffy, A.Dart, A.Taylor. 

European Heart Journal (2013) 34

Plasma Heme oxygenase-1 Level Is Associated With the Presence of Coronary Artery Disease and Unstable Clinical Presentation 

Swati Mukherjee, William Chan, Bronwyn A. Kingwell, Anthony J. White, James A. Shaw, Alaina Natoli, Beth Johnson, Anthony S. Walton, Anthony M. Dart, Stephen J. Duffy 

JACC March 9, 2010 Volume 55, issue 10A 

Ferritin is associated with greater coronary plaque area, positive remodeling and unstable clinical presentation 

S. Mukherjee, B.A. Kingwell, A.J. White, K.D. Croft, H.A. Headlam, J.A. Shaw, A.S. Walton, A.M. 

Dart, S.J. Duffy 

European Heart Journal (2008 ) 29 ( Abstract Supplement ), 585 

Ferritin is Associated with Greater Coronary Plaque Burden, Positive Remodeling and Unstable Clinical Presentation 

S. Mukherjee, B.A. Kingwell, A.J. White, K.D. Croft, H.A. Headlam, A.S. Walton, J.A. Shaw, A.M. Dart, S.J. Duffy 

Accepted for presentation at the Annual Scientific Meeting of The Cardiac Society of Australia and New Zealand 2006.

Heme Oxygenase-1 Genotype is Associated with Coronary Artery Disease in a Caucasian 

Population. 

S. Mukherjee, A.J. White, A. Natoli, B.A. Kingwell, A.S. Walton, A.M. Dart, S.J. Duffy 

Accepted for presentation at the Annual Scientific Meeting of The Cardiac Society of Australia and New Zealand 2006. 

Relationship of Intracoronary Trans-lesional Iron and F2-isoprostanes to Plaque Burden and 

Clinical Presentation 

S. Mukherjee, A.J. White, B.A. Kingwell, K.D. Croft, H.A. Headlam, A.S. Walton, A.M. Dart, S.J. Duffy 

Heart Lung and Circulation 2005;14 (S1): S78 

Matrix metalloproteinase-3 and coronary remodelling: Implications for unstable coronary disease 

Anthony J. White, Stephen J. Duffy, Anthony S. Walton, Jer Fuu Ng, Gregory E. Rice, Swati 

Mukherjee, James A. Shaw, Garry L. Jennings, Anthony M. Dart, Bronwyn A. Kingwell 

Cardiovascular Research 75 (2007) 813–820 

Compliance mismatch between stenotic and distal reference segment is associated with coronary artery disease instability 

Anthony J. White , Stephen J. Duffy , Antony S. Walton, Swati Mukherjee, James A. Shaw, Garry 

L.R. Jennings, Anthony M. Dart, Bronwyn A. Kingwell 

Atherosclerosis (2009) Volume 206, Issue 1, Pages 179-185 

Sodium nitroprusside is an effective treatment for no-reflow during percutaneous intervention for acute myocardial infarction 

L. Reddy, S. Mukherjee, A.S. Walton, A.J. Taylor, A. Broughton, A.M. Dart, S.J. Duffy. 

Heart Lung and Circulation 2005;14 (S1): S138 

Genetic, biochemical and structural determinants of unstable coronary disease 

AJ White, SJ Duffy, AS Walton, S.Mukherjee, AM Dart, GL Jennings and BA Kingwell. 

Heart Lung and Circulation 2005;14 (S1): S78 

Genetic variation in matrix metalloproteinase genes influences risk for coronary artery disease 

AJ White, SJ Duffy, TL Medley, AS Walton, S.Mukherjee, AM Dart, GL Jennings, BA Kingwell. 

Heart Lung and Circulation 2005;14 (S1): S50 

The Safety and Efficacy of Percutaneous Coronary Intervention at a Tertiary Referral Hospital with 

Off-Site Surgical Backup. 

S. Mukherjee, J. Castro ,L. Roberts, L. Johnston, M. Swale, B. Chow, B Collins, G. Proimos, Y.M. 

Cheong, C Goods, M. Rowe. G. New Heart, Lung and Circulation 2004;13S2:S1-132:223 

The Safety and Efficacy of Percutaneous Coronary Intervention for STEMI with Off-Site Surgical 

Backup. 

J. Castro, S. Mukherjee, L. Roberts, L. Johnston, G. Proimos, Y.M. Cheong, C. Goods, M. Rowe, G. New.

Heart, Lung and Circulation 2004;13S2: S1-132:217 

The SHIPEM REGISTRY. Shipping Infarcts for Primary Angioplasty in Eastern Melbourne 

L. Roberts, J. Castro, S. Mukherjee, M. Swale, B. Chou, C. Goods, M. Rowe, G. Proimos, Y.M. 

Cheong, L. Johnston, H. Parker, B. Collins, P. Archer, S. Dilley, G. New. 

Heart, Lung and Circulation 2004;13S2: S1-132:220 

Outcomes from a community-based phase II heart failure (HF) rehabilitation program(RP) 

J. O’Reilly,G. Gordon, L.Worrall-Carter, I. Hansen, J. Castro, S. Mukherjee, B. Chou, M.Swale, T. 

Elmore, G.New 

Heart, Lung and Circulation 2004;13S2: S1-132:120 

Contibution of endothelium dependent hyperpolarisation (via activation of ca-dependent K+ channel) to metabolic vasodilation in the human forearm 

Ziolkowski, J.P.F. Chin-Dusting, N.C. Gollogly, D.K.Vizi, S. Mukherjee, J. McPherson, M. Ralph, and S.J. Duffy

Heart, Lung and Circulation 2004;13S2: S1-132:255 

The Safety and Efficacy of Percutaneous Coronary Intervention at a Tertiary Referral Hospital with Off-Site Surgical Backup. 

K. Lim, P. Garg, J. Castro, S. Mukherjee, L. Roberts, L. Johnston, H. Parker, J. Mariani, G. Proimos, Y.M Cheong, C. Goods, M. Rowe, A. Walton, L. Mc Pherson, C. Dunkley, B. Collins, G. New.

Heart, Lung and Circulation 2004;13:S41:90 

Clinical Research Experience 

Clinical Trials (Co- Investigator)

ASSENT 3 

Efficacy and Safety of Tenecteplase in Combination with Enoxaparin, Abciximab or Unfractionated Heparin: the ASSENT-3 Randomised Trial in Acute Myocardial Infarction. The Assessment of the Safety and Efficacy of a New Thrombolytic Regimen 

SYNERGY Randomized Trial 

Enoxaparin vs Unfractionated Heparin in High-Risk Patients With Non–ST-Segment Elevation Acute Coronary Syndromes Managed With an Intended Early Invasive Strategy 

JAMA. 2004;292:45-54. 

OASIS V 

An International randomised, double-blind study evaluating efficacy and safety of Fondaparanux verusus Enoxaparin in the Acute Treatment of Unstable Angina / Non ST Segment MI Acute Coronary Syndromes 

OASIS VI 

An International randomised, double-blind study evaluating efficacy and safety of Fondaparanux verusus control therapy and glucose-insulin-potassium infusion versus control in a broad range of patients with of St segment elevation AMI 

Centre for Clinical Studies, Alfred Hospital 

A randomized, double-blind, crossover study to evaluate the efficacy and tolerability of a 6 treatment course of GW493838 50mg compared to placebo in dyslipidemic patients with low HDL and elevated TG (Study number: AAD101535). Ethics Project # 80/04. 

(GW493838, a new drug being developed by GlaxoSmithKline)